Tumorigenic describes the capability of a substance, agent, or process to induce or promote the formation of tumors, which are abnormal growths of cells that can be benign or malignant (cancerous). The term is commonly used in the fields of biology, medicine, and toxicology to assess the carcinogenic potential of various factors, including chemicals, radiation, and viruses. Identifying tumorigenic agents is critical for understanding cancer development, implementing preventative measures, and developing effective cancer therapies. Tumorigenicity is often evaluated through in vitro and in vivo studies, involving cell cultures and animal models respectively.
Tumorigenic meaning with examples
- The researchers are investigating whether a newly synthesized chemical compound exhibits tumorigenic properties. Preliminary results suggest that the compound might stimulate uncontrolled cell proliferation in lab-grown cultures, warranting further investigation into its potential carcinogenic effects and associated mechanisms in animal models.
- Chronic exposure to certain types of asbestos has long been known to be tumorigenic in humans, leading to the development of lung cancer and mesothelioma. This understanding has resulted in stricter regulations to minimize exposure and protect individuals from the significant health risks these materials pose.
- The study aimed to determine the tumorigenic effects of a novel viral infection in mice. The animals were monitored for tumor development, and subsequent analysis focused on the virus’s interaction with the host cells, particularly its impact on genes related to cell growth and apoptosis (programmed cell death).
- Researchers evaluated various environmental factors, searching for any tumorigenic factors such as certain pollutants and radiation. Their goal was to establish potential cancer-causing links through examining populations with a higher incidence of specific cancer types in polluted areas, as well as exploring the molecular mechanisms involved.
- Identifying and analyzing the pathways that cause cells to become tumorigenic is critical for developing cancer therapies. Specifically, understanding how these factors affect cell cycle regulation, DNA repair, and immune evasion is essential for designing effective treatments to halt or reverse tumor growth.